- Original Article
- Efficacy of imatinib mesylate-based front-line therapy in pediatric chronic myelogenous leukemia
-
Hyun Jin Oh, Mun Sung Cho, Jae Wook Lee, Pil-Sang Jang, Nack-Gyun Chung, Bin Cho, Hack-Ki Kim
-
Clin Exp Pediatr. 2013;56(8):343-350. Published online August 27, 2013
-
|
Purpose Despite the established role of imatinib (IM) in chronic myelogenous leukemia (CML) in adults, there are few reports on its efficacy in children. In this study, we compared the outcomes of children with CML before and after the advent of IM-based treatment. MethodsThe study cohort consisted of 52 patients treated for CML at the Department of Pediatrics, The Catholic University of... |
-
-
- Utility of a multiplex reverse transcriptase-polymerase chain reaction assay (HemaVision) in the evaluation of genetic abnormalities in Korean children with acute leukemia: a single institution study
-
Hye-Jin Kim, Hyun Jin Oh, Jae Wook Lee, Pil-Sang Jang, Nack-Gyun Chung, Myungshin Kim, Jihyang Lim, Bin Cho, Hack-Ki Kim
-
Clin Exp Pediatr. 2013;56(6):247-253. Published online June 21, 2013
-
|
Purpose In children with acute leukemia, bone marrow genetic abnormalities (GA) have prognostic significance, and may be the basis for minimal residual disease monitoring. Since April 2007, we have used a multiplex reverse transcriptase-polymerase chain reaction tool (HemaVision) to detect of GA. MethodsIn this study, we reviewed the results of HemaVision screening in 270 children with acute leukemia, newly diagnosed at The... |
-
-
- Immune reconstitution after allogeneic hematopoietic stem cell transplantation in children: a single institution study of 59 patients
-
Hyun O Kim, Hyun Jin Oh, Jae Wook Lee, Pil-Sang Jang, Nack-Gyun Chung, Bin Cho, Hack-Ki Kim
-
Clin Exp Pediatr. 2013;56(1):26-31. Published online January 29, 2013
-
|
Purpose Lymphocyte subset recovery is an important factor that determines the success of hematopoietic stem cell transplantation (HSCT). Temporal differences in the recovery of lymphocyte subsets and the factors influencing this recovery are important variables that affect a patient's post-transplant immune reconstitution, and therefore require investigation. MethodsThe time taken to achieve lymphocyte subset recovery and the factors influencing this recovery were investigated... |
-
-
|